Caffeine Metabolism Test

Reasons to take the test:

The DNA test for caffeine metabolism evaluates how quickly an individual metabolizes caffeine and costs only £49. If 2 tests are purchased together discount is £10

Here’s why you should consider taking this test:

1. Understand your response to caffeine: If you are a slow metabolizer, you may experience symptoms such as nausea, tachycardia, insomnia, or hypertension after consuming caffeine.
2. Manage your consumption: Knowing whether you are a fast or slow metabolizer allows you to regulate your caffeine intake more consciously.
3. Reduce the risk of hypertension: Slow metabolizers should limit caffeine intake to avoid increased blood pressure, while fast metabolizers can benefit from moderate consumption.

The test determines whether a person is a fast or slow caffeine metabolizer.

People who metabolize caffeine slowly should reduce or avoid its intake, as they are more prone to developing hypertension. On the other hand, fast metabolizers can consume coffee without issues and are even better protected from this risk with regular consumption. For slow metabolizers, there is a positive and direct correlation between caffeine intake and increased blood pressure, while for fast metabolizers, the relationship is reversed: consuming 4 or more cups of coffee a day can actually reduce the risk of hypertension.

The genetic analysis focuses on the CYP1A2 gene.

This gene encodes the CYP1A2 cytochrome P450 protein, a liver enzyme primarily involved in caffeine metabolism. Caffeine mainly affects the central nervous system by blocking adenosine, a neurotransmitter responsible for the feeling of tiredness when we are not well-rested.

An unfavorable variant of the gene regulating the enzyme can lead to slow caffeine metabolism, prolonging its effects and increasing the risk of developing hypertension.

The sensitivity indication is based on scientific studies that associate the detected genetic variants with a higher likelihood of developing hypertension compared to the general population. This predisposition is a probabilistic factor and does not take into account the individual’s lifestyle, focusing solely on their genetic makeup. As a result, it is not a diagnosis and does not imply a direct cause-effect relationship.

For an example report and the recommendations to follow, click here.

Test procedure:

The test does not require blood, just simple buccal swabs. Once the samples are collected, they can be returned using the pre-addressed envelope provided in the kit.

Results are ready within 5-7 working days and include information on how to manage caffeine consumption based on your genetic predisposition.

Other DNA tests for health:

EasyDNA’s product portfolio includes other DNA testing services that can provide useful insights into various aspects of general health. Take a look at our different DNA Health  tests that can help optimize your well-being  like: 

• Sport DNA test: Discover your ideal sport based on your DNA which includes a comprehensive analysis of your genetic predispositions for power, endurance, recovery, joint resistance, and caffeine metabolism, plus an optional personalized training plan for an additional. Find out more here!
• Know Your BioAge: Find out your reveals your biological age through advanced DNA profiling, empowering you to make informed lifestyle choices for healthier aging and allowing for regular monitoring of your progress. Read more here!
• Gut Microbiome Test:  analyzes your stool sample to assess the health and balance of your gut bacteria, providing personalized dietary recommendations to enhance your gut health, with results delivered via email within 15 to 20 working days. Find out more here!

Disclaimer:The test results are for informational and/or educational purposes only and should NOT be used to make medical, health, or other decisions without consulting a doctor. Always speak with your doctor and seek professional help before taking action. The test does not replace a medical consultation, nor the advice or services of a qualified doctor or other specialist.